Pineapple Juice Attenuates Starvation- Induced Ulceration in Wistar Albino Rats via Antioxidant Mechanisms

Abstract

This study was carried out to examine the effect of pineapple juice on starvation-induced ulceration and gastric mucosal SOD level in Wistar albino rats. The animals were divided into four experimental groups; the Control group (water only) and those pretreated with different percentage of pineapple juice in their water (100, 50, and 25%). The treatment was carried out for 30 days. The animals were fed with rat cubes. Results showed that full pineapple juice significantly decreased mean ulcer scores, an index for the extent of gastric mucosal damage. It also increased Superoxide dismutase activity; this was significantly higher in full juice treated animals than its activities in the other treated groups. We proposed that this represents one of the underlying mechanisms through which pineapple juice may be conferring gastro-protection against starvation-induced ulceration. We therefore conclude that pineapple juice may be therapeutically beneficial to individuals prone to ulcer development.