Cad Spect/Ct in Managing Liver Tumours and Other Related Abnormalities

Abstract

The work evaluates the effect of incorporating OSEM and FBP liver SPECT/CT with a modeled CAD system in managing liver tumors and its relatives. An anthropomorphic torso phantom with lung and liver inserts was injected with ^99mTc. Polystyrene beads filled the lungs inserts. A tumour was mimicked in the liver insert. Sequential SPECT and CT projections were acquired and reconstructed using OSEM and FBP techniques. Segmented and non-segmented SPECT/CT data were modeled and analysed using image j software. Statistical t-test tested the mean grey values of the tumour and its background. The OSEM and FBP reconstructed images were evaluated using contrast to noise ratio (CNR) based on rose criterion. The background and the tumour's mean values were statistically significant. The CNR values for both modeled and non-modeled CAD FBP images were all under the detection range. Nevertheless, its maximum CNR value was at the cutoff frequency 0.48 (1.69). The OSEM reconstructed images displayed peak at 3-4 numbers of iterations. In accession, its modeled CAD evaluation gave CNR values within the detection range from 2-8 numbers of iteration. The non-modeled CAD OSEM reconstructed liver SPECT/CT was below. OSEM was agreed the best in tumour detection and ensuring patient's safety.