A Study on Immunogenetical Factors as Marker of Fibrocalculous Pancreatic Diabetes

Abstract

Fibrocalculous Pancreatic Diabetes (FCPD), is a subset of Malnutrition Related Diabetes. At firstyoung FCPD patients were confirmed clinically for this study. By single radialimmunodiffusion technique IgG, IgA&IgM levels were measured and then lymphocytotoxicity test was performed for detection of HLA –association and compared. Our patient's allhad higher IgG and lower IgA&IgM levels indicating high infection rate and generalized PEM. They require endogenous insulin as  having  positive  first  degree  familial association  and  predisposition  to  type  I diabetes.