Synthesis, Structure Characterization and Antimicrobial Activity of Manganese (II) and Copper (II) Complexes of Isatinphenylhydrazone

Abstract

Mn(II) and Cu(II) complexes of isatinphenylhydrazone, a Schiff base derived from condensation of phenylhydrazine and isatin, (IPH) prepared in a 1:2 molar ratio (metal : ligand). These compounds have been characterized, using elemental analysis, Infrared, electronic absorption spectra and molar conductance measurement. The Infrared spectrum data revealed that the ligand, IPH behaves as a bidentate ligand coordinating to the metal ion using azomethine nitrogen of the hydrazine moiety and carbonyl oxygen of isatinchromophore. From the results of electronic spectra data, tetrahedral geometry was assigned to Mn(II) complex while Cu(II) complex adopt square planar geometry. The antimicrobial activities of the ligand and complexes were done against some bacterial and fungal strains in broth culture. The compounds exhibit moderate inhibitory effect on the microbes.