Synthesis Structural and Biological Studies of Substituted Styryl 1,1-Diphenylmethyl Ketones

Abstract

A series of 1,1-diphenylmethyl chalcones are synthesized from 1,1-diphenylacetone with various substituted benzaldehydes by crossed aldol condensation.  The synthesized chalcones are characterized by their physical constants and spectral data. Antibacterial and anti fungal activities of synthesized chalcones are measured by Kirby-Baury Petri-Disc method. The bacterial strains used are gram positive bacteria Bacillus subtilis, M.luteus and S.aureus gram negative bacteria Escherichia coli, P.aeruginosa and k.pneumonia and anti fungal studies with Aspergillus niger, Tricoderma viride and Mucor species.