Stereochemical Characterization and Antimicrobial Activities of Synthesized Ni (11), Cu (11) and Zn (11) Schiff Base Complexes Derived from P-Nitroaniline and Salicylaldehyde

Abstract

A Schiff base ligand, p-nitroanilinesalicylidene and the corresponding Ni(11), Cu(11) and Zn(11) complexes were obtained from condensation reaction of p-nitroanilinesalicylidene with these metal(11) salts. These synthesized compounds were characterized by the use of elemental analysis, conductometry, magnetic susceptibility, IR, ¹H-NMR and UV-Vis spectroscopy. They were also screened for antimicrobial activities. From the spectral data, the ligand, a monobasic, bidentate molecule became deprotonated and coordinate to the metal ions through the phenolic oxygen and the azomethine nitrogen in a 2: 1 ligand: metal ratio giving square planar to Ni(11) and Cu(11) then tetrahedral geometrical configurations to the Zn(11) complexes. The ligand and the metal complexes exhibited some degree of antimicrobial activities against Staphyloccus aureus, Echerichia coli, Candida albican and Aspergillus Niger.