Exponential Model in Clinical Efficacy of Cryptolepis Sanguinolenta on Faciparum Malaria Treatment

Abstract

Cryptolepis Sanguinolenta is one of the many anti-malaria herbal medicines in Africa, particularly in Ghana. The plant contains Cryptolepis alkaloids when taken orally indicates efficacy in clearing Plasmodium falciparum parasites more than chloroquin. A tea bag of cryptolepis contain 2.5 grams was administered to 50 malaria patients in 5 independent stages. Each stage consist of 10 new patients. An exponential model was used to access probability of healing from uncomplicated malaria within WHO stipulated time for remission. Considering the probability values derived in the assessed overall survival probabilities, we conclude that a patient that faces treatment in stage one will have a 0.6 chance of survival, whereas stages two and three have 0.653 and 0.669 chances of survival respectively. Stages four and five had their overall survival probabilities to be above 0.7 and hence a patient chance of being cured of malaria fever in that stage is 0.7 which is a very high chance of success. It is obvious that uncomplicated malaria has very high chances of being cured with cryptolepis sanguinolenta and hence people affected with malaria are advised to resort to this herbal plant for treatment.