Novel Mode Of Actions (MOAs) Of Marine Cardioactive Biomolecules (MCBs)

Abstract

MCBs have antianginal, antiarrhythmic, antihyperlipidemic, antihypertensive and cardiotonic types of bioactivities. MOAs of  MCBs followed the basic cardiopharmacological  mechanisms. The structural uniqueness of Autonomium chloride, Anthopleurine A, marine toxins and nucleosides imparted new clues of mechanisms. The stereoselective drug action of Octopamine was topographically rationalized.