Antimicrobial Activities of Novel Schiff Base Cu (II) Complex Derived from Glutaraldehyde and L-Histidine

Abstract

Novel metal complex of Cu(II)  with Schiff base derived from Glutaraldehyde  and L-Histidine have been prepared and characterized by magnetic susceptibility, conductance measurement, elemental analyses, UV-Visible, IR, ¹H-NMR spectral studies, powder XRD and TGA. The magnetic and spectroscopic data indicate an octahedral geometry for the complex. The molar conductance measurement indicates that the complex is non-electrolytic in nature. The electronic absorption spectra of the complex shows intraligand and charge transfer transitions. Room temperature magnetic susceptibility measurement reveals that the nature of the complex is paramagnetic. The XRD data shows that the complex is microcrystalline. The antimicrobial activities of ligand and its complex were screened by Disc Diffusion method.